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Step Therapy for Part B Drugs/Devices
Drugs that are injected or infused by your physician in their office, or in a hospital outpatient or ambulatory surgical center are typically covered under your medical (Part B) benefit. Some Part B drugs may require step therapy. Step therapy means that a preferred drug must be tried before a non-preferred drug will be approved by your plan. If you have already been on a non-preferred drug in the previous 365 days, you will not be required to switch to a preferred product, and you may continue using the non-preferred drug.
In Scope Drug Category |
Non-Preferred Drug Products |
Preferred Drug Products |
Anemia (intravenous iron replacement) |
Injectafer Monoferric |
Feraheme Ferrlecit INFed Venofer |
Anti-Nausea Products for Oncology (specifically when used as part of a chemotherapy regimen) |
Akynzeo Cinvanti Sustol |
Aloxi Emend† Granisetron (Kytril) Ondansetron (Zofran) |
Bevacizumab Products (for cancer conditions only) |
Alymsys Avastin Avzivi |
Mvasi† Zirabev† |
Bone Density Agents for Oncology |
Prolia Xgeva |
Ibandronate Pamidronate Zoledronic Acid |
Bone Density Agents for Osteoporosis |
Evenity Prolia |
Ibandronate Pamidronate Zoledronic Acid |
Gemcitabine |
Infugem (J9198) |
Gemcitabine (J9201)† |
Gonadotropin Releasing Hormone Analogs for Oncology |
Leuprolide Acetate 3.75 mg (J1950) |
Leuprolide Acetate 7.5 mg (J1954, J9217)† |
Immune Globulins |
Asceniv Cutaquig Panzyga |
Bivigam† Carimune NF† Cuvitru† Flebogamma DIF† Gammagard† Liquid† Gammagard S/D† Gammaked† Gammaplex† Gamunex-C† Hizentra† HyQvia† Octagam† Privigen† Xembify† |
Immunotherapy for certain cancers - Head and Neck |
Keytruda Opdivo |
Loqtorzi† |
Immunotherapy for certain cancers - Non-Small Cell Lung Cancer |
Opdivo plus Yervoy |
Keytruda† Libtayo† Tecentriq† |
Inflammatory Conditions - Infliximab |
Infliximab Inflectra Remicade |
Avsola Renflexis |
Inflammatory Conditions -Tocilizumab |
Actemra |
Tofidence Tyenne |
Leucovorin/Levoleucovorin |
Fusilev Khapzory Levoleucovorin |
Leucovorin† |
Lupus Agents |
Saphnelo |
Benlysta |
Orthopedic Joint Lubricants |
Euflexxa, Gel-One, Genvisc 850, Hyalgan, Supartz, Supartz FX Synojoynt, Triluron, TriVisc, Visco-3 |
Durolane |
Rituximab Products (for both cancer and non-cancer conditions) |
Riabni Rituxan Rituxan Hycela |
Ruxience† Truxima† |
Trastuzumab Products |
Herceptin Herceptin Hylecta Hercessi Herzuma Ogivri Ontruzant |
Kanjinti† Trazimera† |
Vascular Endothelial Growth Factor (VEGF) Inhibitors (for Age Related Macular Degeneration) |
Beovu Byooviz Cimerli Eylea HD Lucentis Susvimo Vabysmo |
First: Compounded Avastin (bevacizumab) Then: Eylea† |
Vascular Endothelial Growth Factor (VEGF) Inhibitors (for conditions other than Age Related Macular Degeneration) |
Beovu Byooviz Cimerli Eylea HD Lucentis Susvimo Vabysmo |
Eylea† |
White Blood Cell Generation (Short Acting) |
Granix Neupogen Nivestym Nypozi Relueko |
Zarxio† |
White Blood Cell Generation (Long Acting) |
Fulphilia Fylnetra Nyvepria Rolvedon Stimufend Ziextenzo |
Neulasta* Rolvedon* |
*No prior authorization is required for preferred drug products unless the product is marked with a (†) indicating prior authorization is required.
Only certain plans will require step therapy for these Part B drugs. If you are using one of these drugs under the Part B benefit, please contact the customer service center at the phone number on your member ID card to determine if your plan is in scope.